Phloretin – Benefits, Uses, and Side Effects

Phloretin is a natural compound that has gained significant attention due to its potential health benefits. It belongs to the class of flavonoids, which are plant compounds known for their antioxidant and anti-inflammatory properties.
Phloretin is commonly found in fruits such as apples, pears, and grapes. It is responsible for the browning of these fruits when they are exposed to air. Therefore, it can be obtained both through natural dietary sources and as a supplement.
In recent years, there has been a growing interest in the health benefits of phloretin. Research suggests that it may have various positive effects on the body, making it a promising compound in the field of health and wellness.

What is Phloretin?

Phloretin, a flavonoid compound, belongs to a group of naturally occurring plant chemicals known for their antioxidant properties. It is primarily found in the skins of apples and pears, as well as in the roots and barks of some plants. Phloretin is a dihydrochalcone, a type of natural phenol. It can also be found in apple tree leaves and the Manchurian apricot. Phloretin has garnered attention for its potential in various applications, particularly in skincare.

Top Health Benefits of Phloretin

A. Antioxidant Properties
Phloretin's antioxidant properties are supported by scientific evidence. Numerous studies have demonstrated that phloretin exhibits robust antioxidant activity, enabling it to protect the body's cells from damage caused by free radicals. Free radicals are highly reactive molecules that can cause oxidative stress, leading to a wide range of health issues, including aging and chronic diseases.
When free radicals accumulate in the body, they can attack important cellular structures like DNA, lipids, and proteins. This oxidative damage can disrupt cellular function and contribute to the development of conditions such as heart disease, cancer, and neurodegenerative disorders.
Phloretin, however, acts as a potent neutralizer of free radicals, preventing them from causing harm to the body's cells. By reducing oxidative stress, phloretin plays a crucial role in maintaining cellular health and protecting against the development of chronic diseases.

B. Anti-Inflammatory Effects
Research has consistently shown that phloretin possesses significant anti-inflammatory properties. Inflammation is a natural response of the immune system to protect the body from harmful stimuli. However, chronic inflammation can contribute to the development of various diseases, including arthritis and inflammatory bowel disease.
Phloretin inhibits the production of inflammatory molecules in the body, helping to reduce chronic inflammation. By modulating the immune response and suppressing the release of pro-inflammatory mediators, phloretin can help alleviate the symptoms and reduce the risk of chronic inflammatory conditions.

C. Skin Health
Phloretin has gained considerable attention in the skincare industry due to its potential benefits for the skin. Scientific studies support the use of phloretin for improving skin health in multiple ways.
Firstly, phloretin helps protect the skin from damage caused by sun exposure and environmental pollutants. Ultraviolet (UV) radiation from the sun and pollutants in the environment can cause oxidative stress and accelerate skin aging. Phloretin acts as a shield, reducing the harmful effects of UV radiation and environmental pollutants on the skin.
In addition to its protective properties, phloretin has been found to brighten the complexion and reduce hyperpigmentation. By inhibiting certain enzymes involved in melanin production, phloretin can help fade dark spots and create a more even skin tone.
Furthermore, phloretin's antioxidant properties contribute to its anti-aging effects. Oxidative stress is a major factor in the development of wrinkles and fine lines. By neutralizing free radicals and reducing oxidative stress, phloretin helps to diminish the appearance of signs of aging, resulting in smoother, more youthful-looking skin.

D. Weight Management
Emerging research suggests that phloretin may have potential benefits for weight management. Some studies have shown that phloretin can regulate glucose and lipid metabolism, two essential processes for maintaining a healthy weight.
Phloretin has been found to improve insulin sensitivity, which enables cells to effectively take up glucose from the bloodstream. By enhancing insulin sensitivity, phloretin may help regulate blood sugar levels and prevent the accumulation of excess fat.
Additionally, phloretin has been shown to reduce fat accumulation by inhibiting enzymes involved in fat synthesis and promoting the breakdown of fats. These effects may contribute to weight loss and improved body composition.
While further research is needed to fully understand the mechanisms and effects of phloretin on weight management, the existing evidence suggests that it has the potential to aid in maintaining a healthy weight.

In conclusion,  phloretin offers a range of health benefits supported by scientific evidence. Its antioxidant properties protect cells from damage, its anti-inflammatory effects help reduce the risk of chronic inflammatory conditions, and it provides numerous benefits for skin health. Additionally, preliminary research suggests that phloretin may have a role in weight management. Incorporating phloretin into skincare routines or consuming it as a dietary supplement may provide significant advantages for overall well-being.

Uses of Phloretin

A. Dietary Supplement
Phloretin is not only found in fruits like apples, pears, and cherries but is also available as a dietary supplement in the form of capsules or powders. The scientific evidence behind phloretin's antioxidant properties is robust. A study published in the Journal of Agricultural and Food Chemistry found that phloretin exhibits strong antioxidant activity, effectively neutralizing harmful free radicals in the body (Kessler et al., 2003). By reducing oxidative stress, phloretin may help protect cells from damage and support overall health and wellness.
Furthermore, phloretin has been associated with anti-aging benefits. A study published in the journal Planta Medica demonstrated that phloretin inhibits collagenase, an enzyme responsible for collagen breakdown. Collagen is essential for maintaining skin elasticity and firmness. By preserving collagen, phloretin may contribute to a more youthful and vibrant appearance (Walter et al., 2010). These findings support the marketing claims of phloretin as an anti-aging dietary supplement.

B. Skincare Products
Phloretin's potential benefits extend beyond its use as a dietary supplement. It is widely utilized in various skincare products, including serums, creams, and lotions. The scientific evidence supporting phloretin's role in skincare is compelling.

One of phloretin's primary mechanisms of action in skincare is its ability to combat oxidative damage. Research published in the Journal of Photochemistry and Photobiology B: Biology demonstrates that phloretin protects skin cells against damage caused by reactive oxygen species, effectively reducing inflammation and preventing premature aging (Shih et al., 2009). By neutralizing free radicals, phloretin helps to maintain a healthier and more youthful complexion.

Not only does phloretin shield the skin from oxidative damage, but it also exhibits skin-brightening properties. A study published in the Journal of Cosmetic Dermatology reveals that phloretin inhibits tyrosinase, an enzyme involved in the production of melanin. By reducing melanin synthesis, phloretin can help minimize the appearance of dark spots and uneven skin tone, resulting in a brighter complexion (Nebus et al., 2011).

Additionally, phloretin has shown efficacy in improving the signs of aging. A study published in the International Journal of Cosmetic Science found that phloretin stimulates collagen production and inhibits matrix metalloproteinases, enzymes responsible for collagen degradation. This dual action promotes firmer skin with reduced fine lines and wrinkles (Adil et al., 2017).

Incorporating phloretin into skincare products may harness these scientifically proven benefits, contributing to healthier, brighter, and more youthful-looking skin. It is important to note that further research is still necessary to fully understand the mechanisms and long-term effects of phloretin in skincare.

How to Incorporate Phloretin into Your Skincare Routine

Phloretin can be incorporated into your skincare routine in various ways to maximize its benefits for the skin. Scientific studies recommend the following steps:
Cleanse:  Begin by cleansing your face using a gentle cleanser suitable for your skin type. This helps to remove dirt, oil, and impurities, preparing the skin for the absorption of phloretin.

Tone:  After cleansing, use a toner to balance the skin's pH levels and enhance its receptiveness to the active ingredients present in phloretin. Look for a toner that is alcohol-free and contains soothing botanical extracts.

Apply Phloretin Serum:  The best way to incorporate phloretin into your routine is by applying a serum containing a high concentration of phloretin. This allows for direct and targeted application to the skin. Take a few drops of the serum and gently massage it onto the face, neck, and décolletage, ensuring even distribution.

Moisturize:  Follow up with a moisturizer to lock in the benefits of phloretin and provide optimal hydration to the skin. Look for a moisturizer that is lightweight, non-comedogenic, and suitable for your skin type.

Sun Protection:  In order to enhance the protective effects of phloretin against UV damage, it is crucial to use a broad-spectrum sunscreen with a high SPF. Apply generously and reapply every two hours, especially when exposed to direct sunlight.

By following these steps, you can incorporate phloretin into your skincare routine effectively, ensuring maximum absorption and efficacy. Consistency is key, so make sure to use phloretin-based products consistently to experience noticeable improvements in your skin's appearance and health.

Potential Side Effects and Precautions of Using Phloretin

While phloretin is generally considered safe, it is important to be aware of potential side effects and take necessary precautions when using it in your skincare routine. Although rare, some individuals may experience the following:

Skin Sensitivity:  In some cases, phloretin may cause slight skin sensitivity, especially for individuals with extremely sensitive skin. If you experience redness, irritation, or discomfort after applying phloretin, discontinue use and consult a dermatologist.

Allergic Reactions:  Although uncommon, allergic reactions to phloretin can occur in sensitive individuals. These may manifest as itching, swelling, or a rash. It is advisable to conduct a patch test before applying phloretin all over your face to check for any adverse reactions.

Sun Sensitivity:  When using phloretin, it is crucial to apply sunscreen regularly, as it may increase the skin's sensitivity to sunlight. Phloretin protects against UV damage but does not replace the need for proper sun protection.

To minimize the risk of side effects, it is important to follow the manufacturer's instructions and use phloretin-based products as recommended. If you have any underlying skin conditions or concerns, it is advisable to consult a dermatologist before incorporating phloretin into your skincare routine.

Phloretin vs. Other Antioxidants: A Comparative Analysis

Phloretin has gained recognition as a powerful antioxidant, but how does it compare to other antioxidants commonly found in skincare products? Let's examine a comparative analysis:

Vitamin C (Ascorbic Acid):  Both phloretin and vitamin C exhibit potent antioxidant effects, protecting the skin against free radical damage. However, phloretin demonstrates enhanced stability compared to ascorbic acid, making it less prone to oxidation and degradation. This ensures a longer shelf life and increased efficacy in phloretin-based skincare products.

Vitamin E (Tocopherol):  Similar to phloretin, vitamin E is a powerful antioxidant that scavenges free radicals and protects against oxidative stress. The combination of phloretin and vitamin E can provide synergistic effects, offering enhanced antioxidant protection and increased stability.

Resveratrol:  Resveratrol, derived from grapes and other plants, is known for its antioxidant and anti-inflammatory properties. While both phloretin and resveratrol have comparable antioxidant effects, phloretin offers additional benefits such as skin brightening and UV protection, making it a more versatile ingredient in skincare formulations.

Green Tea Extract:  Green tea extract is rich in polyphenols, which possess antioxidant and anti-inflammatory properties. Phloretin, when combined with green tea extract, can enhance the overall antioxidant efficacy, providing increased protection against free radicals and promoting healthier skin.

It's important to note that different antioxidants may complement one another, leading to synergistic effects and enhanced protection against oxidative stress. By incorporating a combination of antioxidants, including phloretin, into your skincare routine, you can benefit from a comprehensive antioxidant shield, combating the signs of aging, and promoting overall skin health.

Where to Buy Phloretin: Your Ultimate Shopping Guide

When looking to purchase phloretin-based skincare products, here are some important considerations and shopping tips:
Research Reputable Brands:  Look for established skincare brands known for their commitment to quality and use of scientifically-backed ingredients. Conduct thorough research to ensure the brand's credibility and reputation among skincare enthusiasts.

Read Product Labels:  Check the ingredient list of the skincare products you are considering to verify the presence and concentration of phloretin. Look for products that contain a significant amount of phloretin to ensure maximum efficacy.

Seek Professional Advice:  If unsure about which phloretin product to choose, consult a dermatologist or skincare professional. They can recommend specific products based on your skin type, concerns, and desired effects.

Read Customer Reviews:  Take the time to read reviews from customers who have used phloretin-based products. These reviews can provide valuable insights into the effectiveness, suitability, and overall experience with the product.

Purchase from Authorized Retailers:  To ensure the authenticity and quality of phloretin products, purchase directly from authorized retailers or the brand's official website. Avoid purchasing from unauthorized sources to minimize the risk of counterfeit or diluted products.

By following these tips, you can navigate through the purchasing process and find reliable sources for high-quality phloretin-based skincare products, ensuring that you obtain genuine products that deliver the desired benefits to your skin.


Phloretin Powder Manufacturer-Bioway Organic, Since 2009 

Bioway Organic is known for its expertise and experience in producing high-quality phloretin powder.
Phloretin powder is a valuable ingredient used in various industries, including dietary supplements and skincare products. As a reputable manufacturer, Bioway Organic ensures that their phloretin powder is produced using top-of-the-line manufacturing processes and adheres to strict quality control standards.

Bioway Organic's commitment to organic production methods makes it a reliable source for customers seeking natural and eco-friendly ingredients. By prioritizing organic practices, they strive to deliver phloretin powder that is free from harmful chemicals and pesticides, ensuring the purity and safety of their products.

With over a decade of experience, Bioway Organic has established itself as a trusted supplier in the industry. Their continuous focus on research and development enables them to stay at the forefront of phloretin powder production, offering innovative solutions to meet the evolving needs of their customers.

Whether you are a dietary supplement manufacturer or a skincare product brand, partnering with Bioway Organic as your phloretin powder manufacturer can provide you with the assurance of high-quality products, backed by their years of expertise and dedication to customer satisfaction.

Contact Us:
Grace HU (Marketing Manager)
Carl Cheng ( CEO/Boss ):

Post time: Nov-20-2023