Camptotheca Acuminata Extract

CAS NO: 7689-03-4
Molecular Formula: C20H16N2O4
Molecular Weight: 348.3
Specification: 98% Camptothecin Powder
Features: High Purity, Natural and Botanical Source, Topoisomerase I Inhibitor, Potent Anti-Cancer Activity, Versatile Application, Research-grade Quality
Application: Cancer treatment, Drug synthesis, Research and development, Biotechnology, Herbal medicine, Natural cosmetics, Agriculture

 

 

 


Product Detail

Product Tags

Product Introduction

Camptotheca acuminata extract is a concentrated form of the compound camptothecin, derived from the bark and leaves of the Camptotheca acuminata tree. The extract is processed to contain 98% min pure camptothecin powder. Camptothecin is a naturally occurring alkaloid that has shown promising anticancer properties. It works by inhibiting the activity of the enzyme topoisomerase, which is involved in DNA replication and cell division. Research has demonstrated that camptothecin can effectively target and kill cancer cells. Therefore, the extract is often used in the development of chemotherapy drugs and other pharmaceutical treatments for various types of cancer. However, it is important to note that camptothecin is a potent compound and should only be used under the supervision and guidance of medical professionals.

Specification

Product Name Camptothecin Shelf Life 2 years
Part Used root Appearance light yellow fine powder
Specification 98%
Storage Store in a well-closed container away from moisture and direct sunlight
Shelf Life 36 months if sealed and stored properly
Sterilization Method High-temperature, non-irradiated.

 

Item Specification Test result
Physical Control
Appearance light pink powder Conforms
Odor Characteristic Conforms
Taste Characteristic Conforms
Part Used leave Conforms
Loss on Drying ≤5.0% Conforms
Ash ≤5.0% Conforms
Production Method Supercritical CO2 Extraction Conforms
Allergens None Conforms
Chemical Control
Heavy metals NMT 10ppm Conforms
Arsenic NMT 2ppm Conforms
Lead NMT 2ppm Conforms
Cadmium NMT 2ppm Conforms
Mercury NMT 2ppm Conforms
GMO Status GMO-Free Conforms
Microbiological Control
Total Plate Count 10,000cfu/g Max Conforms
Yeast & Mold 1,000cfu/g Max Conforms
E.Coli Negative Negative
Salmonella Negative Negative

Features

(1) High concentration:  Contains 98% pure camptothecin powder.
(2) Natural origin:  Extracted from Camptotheca acuminata, a tree native to China.
(3) Anticancer properties: Camptothecin has demonstrated strong anticancer activity.
(4) Chemotherapeutic compound: Used in targeted cancer therapies.
(5) Potent antitumor agent:  Effective in inhibiting the growth of tumors.
(6) Promotes cancer cell death:  Induces apoptosis in cancer cells.
(7) Alternative to traditional treatments:  Offers a natural approach to cancer therapy.
(8) Potential anti-tumor natural product: Considered for further research and development.
(9) Powerful antioxidant:  Helps to combat oxidative stress and reduces cellular damage.
(10) Safety and quality assurance: Manufactured under strict quality control standards.

Health Benefits

(1) Anti-cancer properties:  Camptothecin, the primary active compound in camptotheca acuminata extract, has shown promising anti-cancer activity in preclinical studies. It inhibits the enzyme topoisomerase I, which is involved in DNA replication and transcription, ultimately resulting in the inhibition of cancer cell growth.

(2) Antioxidant activity:  Camptotheca acuminata extract has been found to possess antioxidant activity, which helps neutralize harmful free radicals in the body. Antioxidants can contribute to overall health by protecting cells from damage caused by oxidative stress.

(3) Anti-inflammatory effects:  Some studies have suggested that camptotheca acuminata extract may possess anti-inflammatory properties. Inflammation is associated with various chronic diseases, and reducing inflammation can potentially have a positive impact on overall health.

(4) Anti-viral activity: Preliminary research has indicated that camptotheca acuminata extract, specifically camptothecin, may exhibit antiviral properties. It has shown inhibitory effects against certain viruses, including herpes simplex virus and human cytomegalovirus.

Application

(1) Camptotheca acuminata extract is commonly used in traditional Chinese medicine for its anti-cancer properties.
(2) It contains camptothecin, a natural compound that inhibits the replication of cancer cells.
(3) It has been used in chemotherapy treatments for certain types of cancer, including lung, ovarian, and colorectal cancers.
(4) It has also shown potential in treating brain tumors and leukemia.
(5) The extract has antioxidant properties and may help protect against oxidative stress and DNA damage.
(6) Studies have shown that Camptotheca acuminata extract may have anti-inflammatory effects, making it beneficial for conditions such as arthritis and inflammatory bowel disease.
(7) It is also being researched for its potential in treating HIV and hepatitis.
(8) It is used in skincare products for its ability to promote collagen production and improve skin elasticity.
(9) It has been used traditionally for its analgesic properties to relieve pain.
(10) The extract is still an active area of research, and further studies are needed to explore its potential in various medical applications.

Production Details (Flow Chart)

(1) Harvesting:  The Camptotheca acuminata plant is harvested at the appropriate stage when the camptothecin content is high.
(2) Drying: The harvested plant material is dried using a suitable method, such as air drying or drying with the help of heat.
(3) Grinding: The dried plant material is finely ground into a powder using grinding equipment.
(4) Extraction:  The ground powder is subjected to an extraction process using a suitable solvent, often a combination of water and organic solvents.
(5) Filtration:  The extracted solution is filtered to remove any solid impurities or plant residues.
(6) Concentration: The filtered solution is concentrated under reduced pressure or by evaporating the solvent to increase the concentration of camptothecin.
(7) Purification:  Further purification techniques, such as chromatography, crystallization, or solvent partitioning, may be employed to isolate and purify camptothecin.
(8) Drying: The purified camptothecin is dried to remove any residual moisture.
(9) Milling: The dried camptothecin is milled to obtain a finely powdered form.
(10) Quality Control: The final product is subjected to rigorous quality control tests to ensure it meets the desired specifications of 98% camptothecin.
(11) Packaging: The resulting 98% camptothecin powder is packed in suitable containers, ready for distribution or further processing.

Packaging and Service

Storage: Keep in a cool, dry, and clean place, Protect from moisture and direct light.
Bulk Package: 25kg/drum.
Lead Time: 7 days after your order.
Shelf Life: 2 years.
Remark: Customized specifications also can be achieved.

Payment and Delivery Methods

Express
Under 100kg, 3-5Days
Door to door service easy to pick up the goods

By Sea
Over300kg, Around 30 Days
Port to port service professional clearance broker needed

By Air
100kg-1000kg, 5-7Days
Airport to airport service professional clearance broker needed

trans

Certification

Camptotheca Acuminata Extract is certified with the ISO certificate, HALAL certificate, and KOSHER certificate.

CE

FAQ (Frequently Asked Questions)

What are the Side Effects of Camptotheca Acuminata Extract (with 98% Camptothecin Powder)?

Nausea and vomiting: Camptothecin itself can cause gastrointestinal disturbances, including nausea and vomiting. These side effects can be managed with antiemetic medications.

Diarrhea:  Diarrhea is another common side effect of camptothecin. Adequate hydration and appropriate anti-diarrheal medications may be necessary to manage this side effect.

Myelosuppression:  Camptothecin can suppress the bone marrow and affect the production of blood cells, leading to a decrease in red and white blood cells and platelets. This can result in anemia, increased susceptibility to infections, and an increased risk of bleeding. Regular blood tests are needed to monitor blood cell counts during treatment.

Fatigue:  Fatigue is a common side effect of many chemotherapy drugs, including camptothecin. It is important to rest and conserve energy during treatment.

Hair loss:  Camptothecin can cause hair loss, including scalp, body, and facial hair.

Risk of infection:  Camptothecin can weaken the immune system, increasing the risk of infection. It is important to take precautions to minimize the risk of exposure to infectious agents during treatment.

Allergic reactions:  Some individuals may experience allergic reactions to camptotheca acuminata extract. Symptoms can range from mild to severe and may include rash, itching, shortness of breath, and swelling. Immediate medical attention should be sought in case of a severe allergic reaction.

Liver toxicity:  Camptothecin can cause liver toxicity, leading to elevated liver enzymes and potential liver damage. Liver function tests should be regularly monitored during treatment.

Hypersensitivity reactions:  Rarely, individuals may experience hypersensitivity reactions to camptothecin, which can include symptoms such as fever, chills, and difficulty breathing. Immediate medical assistance should be sought if these symptoms occur.

It is essential to discuss any potential side effects and precautions with a healthcare professional before starting any treatment with camptotheca acuminata extract. They can provide personalized advice based on individual medical history and the specific formulation of the extract being used.


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